Systems glycobiology enabled by innovations in mass spectrometry and chemical biology
Glycosylation is a dominant feature of extracellular phenotypes. Glycoproteins present distinct combinations of glycans and amino acids that create unique molecular surfaces to relay biological information in a language called the glycocode. Despite evidence that the glycocode orchestrates numerous aspects of cell surface biology, we lack a fundamental understanding of the glycosylation landscape across the proteome, largely because we do not have tools to capture the glycocode at a systems level. Our group works to address this critical gap in current analytical technology to study glycocode regulation across biological networks that govern health and disease.
Latest News
2024.08.29
RRG has a new preprint out! Improvements in glycoproteomics
through architecture changes to the Orbitrap Tribrid MS platform
Congrats Tim, Emmajay, Ruby, Kayla, and Anna!
2024.08.26
RRG has a new preprint out! Autonomous Dissociation-Type
Selection for Glycoproteomics using Real-Time Library Search
Congrats Emmajay, Tim, Jacob, and Katie!
2024.08.23
Vishnu has his last day in-person with RRG before beginning
fall courses at UC Berkeley. Good luck this year, Vishnu!
2024.08.15
Adrian gives a final presentation for the SCROCCS program
and has his last day in the RRG. We enjoyed having you in the
group and will miss you, Adrian. Good luck with your fall
semester back at Pierce College!
2024.08.06
Nick is highlighted in the "Meet the Glycoscientist" section of
the Fall 2024 newsletter from the American Chemical Society
Division of Carbohydrate Chemistry & Chemical Glycobiology (CARB)
2024.07.23
Katie wins first place for her poster at Cascadia
Proteomics Symposium 2024! Congrats, Katie!
2024.07.23
Jacob and Nick give talks, and Haley gives a flash talk at
Cascadia Proteomics Symposium 2024!
2024.07.22
Daniel gives a talk and Katie gives a flash talk at Cascadia
Proteomics Symposium 2024!
2024.07.22 thru 2024.07.23
RRG attends Cascadia Proteomics Symposium 2024
at the Institute for Systems Biology in SLU.
2024.07.01
Anna receives the Member-at-Large Educational Reentry Award given by
the National Honor Society for Women in Chemistry. Congrats, Anna!
2024.06.26
Daniel attends FASEB conference in Southbridge, MA and
presents a talk on KRAS phosphorylation that drives cell invasiveness.
2024.06.20
Research Intern Vishnu Rajan joins us for an
internship experience. Welcome, Vishnu!
2024.06.17
Undergraduate student Adrian Tarroza joins us for a summer internship
through SCROCCS. Summer rotator Leah McDermott begins
her rotation with RRG. Welcome, Adrian and Leah!
2024.06.11
Graduate student Daniel Gómez Zepeda joins us for a
summer internship. Welcome, Daniel!
2024.06.11
Dr. Haley Schramm begins her first day as a postdoc in the group.
She finished her Ph.D. in Chemistry with Prof. Brian Clowers at Washington
State University. Welcome, Haley! We are excited to have you here!
2024.06.07
The South Carolina Honors colleges publishes a piece titled
"Investigating the Interfaces" that highlights Nick as the SCHC
2023 Distinguished Young Honors Alumni awardee.
2024.06.06
Kayla, Jacob, Anna, and Katie present their posters in the
Glycoproteins II session at ASMS 2024. They also did a great job!
2024.06.05
Ruby, Emmajay, and Tim present their posters in the
Glycoproteins I session at ASMS 2024. They did a great job!
2024.06.04
Nick receives the ASMS Research Award during the
Tuesday Award ceremony at ASMS.
2024.06.03
Nick presents a talk in the Glycopeptides, Glycoproteins,
and Glycomics session at ASMS 2024 in Anaheim.
2024.06.01
The RRG travels to Anaheim for ASMS 2024 and makes
a Saturday pitstop at Disneyland before the conference begins!
2024.05.30
Nick presents at the Quantitative Biosciences Institute-Rezo Therapeutics
Mass Spectrometry Symposium on Emerging Proteomic Technologies
to Address Outstanding Biological Challenges.
2024.05.28
Nick is interviewed by LCGC International Magazine
to highlight his upcoming ASMS 2024 talk.
2024.05.13
Our first publication as a group, a review titled "Instrumentation
at the Leading Edge of Proteomics", is published in Analytical Chemistry!
2024.05.07
Emmajay, Tim, and Nick present as the featured speakers
at the PacMass Spring 2024 meeting.
2024.04.26
Nick visits the Complex Carhohydrate Research Center
and UGA's Department of Biochemistry and Molecular Biology
to present a seminar.
2024.04.19
Our review on Instrumentation at the Leading Edge of Proteomics
is accepted by Analytical Chemistry! Check out the pre-print
version at ChemRxiv. Congrats all!
2024.04.11 thru 2024.04.14
Nick attends the Scialog Conference on Automating
Chemical Laboratories as a Scialog Fellow.
2024.04.02
Collaborative work involving the Riley Research Group
and led by the Polyak group at Harvard Medical School
is accepted for publication in PNAS. Congrats all!
2024.03.25
The Spring Quarter 2024 begins! Nick is teaching
CHEM 428/528 Biomolecular Analysis and
2024.03.22
ASMS announces that Nick is one of the
recipients of the 2024 Research Awards!
2024.03.10 thru 2024.03.13
Nick and Emmajay attend US HUPO 2024 in Portland, OR. Nick presents at the workshop
on Creativity in Scientific Communication during Early Career Researcher Mentoring Day
and gives a talk in the Functional Characterization of the Proteome parallel session.
Emmajay does an awesome job presenting a lightning talk and her poster.
She even won an Honorable Mention in the lightning talk competition!
See News and Updates for more!
Our Philosophy
We are a lab committed to quality science and a supportive lab environment. Collaboration and mentorship are themes of our group,
and we aim to make sure everyone has the opportunity to pursue their goals in research and beyond.
